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PUBLICATIONS

2024

Runda, Michael E.; Miao, Hui; de Kok, Niels A. W.; Schmidt, Sandy

Developing Hybrid Systems to Address O2 Uncoupling in Multi-Component Rieske Oxygenases Journal Article

In: bioRxiv, vol. 2024.02.16.580709, 2024, (This article is a preprint and has not been certified by peer review).

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Terholsen, Henrik; Schmidt, Sandy

Cell-free chemoenzymatic cascades with bio-based molecules Journal Article

In: Current Opinion in Biotechnology, vol. 85, pp. 103058, 2024, ISSN: 0958-1669.

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Schröder, Simon; Maier, Artur; Schmidt, Sandy; Mügge, Carolin; Tischler, Dirk

Enhancing biocatalytical N-N bond formation with the actinobacterial piperazate synthase KtzT Journal Article

In: Molecular Catalysis, vol. 553, no. 113733, pp. 11, 2024, ISSN: 2468-8231.

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2023

Grandi, Eleonora; Özgen, Fatma Feyza; Schmidt, Sandy; Poelarends, Gerrit J

Enzymatic Oxy- and Amino-Functionalization in Biocatalytic Cascade Synthesis: Recent Advances and Future Perspectives Journal Article

In: Angewandte Chemie International Edition, vol. n/a, no. n/a, pp. e202309012, 2023, ISSN: 1433-7851.

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Runda, Michael E.; Kok, Niels A. W.; Schmidt, Sandy

Cover Feature - Rieske Oxygenases and Other Ferredoxin-Dependent Enzymes: Electron Transfer Principles and Catalytic Capabilities Journal Article

In: ChemBioChem, vol. e202300466, 2023, ISSN: 14397633.

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Runda, Michael Ernst; Kremser, Bastian; Özgen, Feyza; Schmidt, Sandy

An Optimized System for the Study of Rieske Oxygenase-catalyzed Hydroxylation Reactions In vitro Journal Article

In: ChemCatChem, vol. e202300371, 2023, ISBN: 2013206534.

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Alphand, Véronique; Berkel, Willem J H Van; Jurkaš, Valentina; Kara, Selin; Kourist, Robert; Kroutil, Wolfgang; Mascia, Francesco; Nowaczyk, Marc M; Paul, Caroline E; Schmidt, Sandy; Spasic, Jelena; Tamagnini, Paula; Winkler, Christoph K.

Exciting Enzymes: Current State and Future Perspective of Photobiocatalysis Journal Article

In: ChemPhotoChem, vol. 202200325, 2023.

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Runda, Michael E; Schmidt, Sandy

Light-driven bioprocesses Journal Article

In: Physical Sciences Reviews, pp. 1–34, 2023.

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Runda, Michael Ernst; Kok, Niels A W; Schmidt, Sandy

Rieske Oxygenases and other Ferredoxin-dependent Enzymes: Electron Transfer Principles and Catalytic Capabilities Journal Article

In: ChemBioChem, pp. e202300078, 2023, ISSN: 1439-4227.

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Kok, Niels A W De; Schmidt, Sandy

Tapping into abiological reaction chemistries in biocatalysis Journal Article

In: Chem Catalysis, no. 2022, pp. 100493, 2023, ISSN: 2667-1093.

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2022

Schmidt, Sandy

Photoexcited enzymes for asymmetric Csp3-Csp3 cross-electrophile couplings Journal Article

In: Angewandte Chemie International Edition, vol. n/a, no. n/a, 2022.

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Özgen, Fatma Feyza; Jorea, Alexandra; Capaldo, Luca; Kourist, Robert; Ravelli, Davide; Schmidt, Sandy

Cover Picture - The Synthesis of Chiral gamma-Lactones by Merging Decatungstate Photocatalysis with Biocatalysis Journal Article

In: ChemCatChem, 2022, ISSN: 18673899.

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Schmidt, Sandy

Expanding the repertoire of Rieske oxygenases for O-demethylations Journal Article

In: Chem Catalysis, vol. 2, no. 8, pp. 1843–1845, 2022, ISSN: 2667-1093.

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Özgen, Fatma Feyza; Jorea, Alexandra; Capaldo, Luca; Kourist, Robert; Ravelli, Davide; Schmidt, Sandy

The Synthesis of Chiral gamma-Lactones by Merging Decatungstate Photocatalysis with Biocatalysis Journal Article

In: ChemCatChem, vol. n/a, no. n/a, 2022, ISSN: 1867-3880.

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Kristina, Haslinger; Sandy, Schmidt

Späte Funktionalisierung mit Biokatalysatoren aus Naturstoffsynthesen Journal Article

In: Nachrichten aus der Chemie, no. August, pp. 62-65, 2022.

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2021

Özgen, Fatma Feyza; Runda, Michael E.; Schmidt, Sandy

Photo-biocatalytic Cascades: Combining Chemical and Enzymatic Transformations Fueled by Light Journal Article

In: ChemBioChem, vol. 22, no. 5, pp. 790–806, 2021, ISSN: 14397633.

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Kourist, Robert; Schmidt, Sandy (Ed.)

The Autotrophic Biorefinery: Raw Materials from Biotechnology Book

De Gruyter, 2021, ISBN: 9783110550603.

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Schmidt, Sandy; Schallmey, Anett; Kourist, Robert

Multi-Enzymatic Cascades In Vitro Book Section

In: Kara, Selin; Rudroff, Florian (Ed.): Enzyme Cascade Design and Modelling, pp. 31–48, Springer International Publishing, Cham, 2021, ISBN: 9783030657185.

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Schmidt, Sandy

Applications of mixed microbial cultures in industrial biotechnology Book Chapter

In: Kourist, Robert; Schmidt, Sandy (Ed.): The Autotrophic Biorefinery, pp. 353–384, De Gruyter, Berlin, Boston, 2021.

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2020

Schmidt, Sandy; Bornscheuer, Uwe T.

Baeyer-Villiger monooxygenases: From protein engineering to biocatalytic applications Book Section

In: Chaiyen, Pimchai; Tamanoi, Fuyuhiko B T - The Enzymes (Ed.): Enzymes, vol. 47, pp. 231–281, Academic Press, 2020, ISSN: 18746047.

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Büchsenschütz, Hanna C.; Vidimce-Risteski, Viktorija; Eggbauer, Bettina; Schmidt, Sandy; Winkler, Christoph K.; Schrittwieser, Joerg H.; Kroutil, Wolfgang; Kourist, Robert

Stereoselective Biotransformations of Cyclic Imines in Recombinant Cells of Synechocystis sp. PCC 6803 Journal Article

In: ChemCatChem, vol. 12, no. 3, pp. 726–730, 2020, ISSN: 18673899.

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Özgen, F. Feyza; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy

Artifizielle Lichtsammelkomplexe ermöglichen Rieske‐Oxygenase‐ katalysierte Hydroxylierungen in nicht‐photosynthetischen Zellen Journal Article

In: Angewandte Chemie, vol. 132, no. 10, pp. 4010–4016, 2020, ISSN: 0044-8249.

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Özgen, F. Feyza; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy

Artificial Light-Harvesting Complexes Enable Rieske Oxygenase Catalyzed Hydroxylations in Non-Photosynthetic cells Journal Article

In: Angewandte Chemie - International Edition, vol. 59, no. 10, pp. 3982–3987, 2020, ISSN: 15213773.

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2019

Schweiger, Anna K.; Ríos-Lombardía, Nicolás; Winkler, Christoph K.; Schmidt, Sandy; Morís, Francisco; Kroutil, Wolfgang; González-Sabín, Javier; Kourist, Robert

Using Deep Eutectic Solvents to Overcome Limited Substrate Solubility in the Enzymatic Decarboxylation of Bio-Based Phenolic Acids Journal Article

In: ACS Sustainable Chemistry and Engineering, vol. 7, no. 19, pp. 16364–16370, 2019, ISSN: 21680485.

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Assil-Companioni, Leen; Schmidt, Sandy; Heidinger, Petra; Schwab, Helmut; Kourist, Robert

Hydrogen-Driven Cofactor Regeneration for Stereoselective Whole-Cell C=C Bond Reduction in Cupriavidus necator Journal Article

In: ChemSusChem, vol. 12, no. 11, pp. 2361–2365, 2019, ISSN: 1864564X.

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Schmermund, Luca; Jurkaš, Valentina; Özgen, F. Feyza; Barone, Giovanni D.; Büchsenschütz, Hanna C.; Winkler, Christoph K.; Schmidt, Sandy; Kourist, Robert; Kroutil, Wolfgang

Photo-Biocatalysis: Biotransformations in the Presence of Light Journal Article

In: ACS Catalysis, vol. 9, no. 5, pp. 4115–4144, 2019, ISSN: 21555435.

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Özgen, Fatma Feyza; Schmidt, Sandy

Rieske non-heme iron dioxygenases: Applications and future perspectives Book Section

In: Husain, Qayyum; Ullah, Mohammad Fahad (Ed.): Biocatalysis: Enzymatic Basics and Applications, pp. 57–82, Springer International Publishing, Cham, 2019, ISBN: 9783030250232.

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Zhang, Wuyuan; Fueyo, Elena Fernandez; Hollmann, Frank; Martin, Laura Leemans; Pesic, Milja; Wardenga, Rainer; Höhne, Matthias; Schmidt, Sandy

Combining Photo-Organo Redox- and Enzyme Catalysis Facilitates Asymmetric C-H Bond Functionalization Journal Article

In: European Journal of Organic Chemistry, vol. 2019, no. 1, pp. 80–84, 2019, ISSN: 10990690.

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2018

Fiorentini, Filippo; Hatzl, Anna Maria; Schmidt, Sandy; Savino, Simone; Glieder, Anton; Mattevi, Andrea

The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases Journal Article

In: Biochemistry, vol. 57, no. 48, pp. 6701–6714, 2018, ISSN: 15204995.

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Dong, Jia Jia; Fernández-Fueyo, Elena; Hollmann, Frank; Paul, Caroline E.; Pesic, Milja; Schmidt, Sandy; Wang, Yonghua; Younes, Sabry; Zhang, Wuyuan

Biocatalytic Oxidation Reactions: A Chemist's Perspective Journal Article

In: Angewandte Chemie - International Edition, vol. 57, no. 30, pp. 9238–9261, 2018, ISSN: 15213773.

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Dong, JiaJia; Fernández-Fueyo, Elena; Hollmann, Frank; Paul, Caroline E.; Pesic, Milja; Schmidt, Sandy; Wang, Yonghua; Younes, Sabry; Zhang, Wuyuan

Biokatalytische Oxidationsreaktionen - aus der Sicht eines Chemikers Journal Article

In: Angewandte Chemie, vol. 130, no. 30, pp. 9380–9404, 2018, ISSN: 1521-3757.

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Schmidt, Sandy; Castiglione, Kathrin; Kourist, Robert

Overcoming the Incompatibility Challenge in Chemoenzymatic and Multi-Catalytic Cascade Reactions Journal Article

In: Chemistry - A European Journal, vol. 24, no. 8, pp. 1755–1768, 2018, ISSN: 15213765.

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Schmidt, Sandy; Dörr, Mark; Bornscheuer, Uwe T.

Library growth and protein expression: Optimal and reproducible microtiter plate expression of recombinant enzymes in E. coli using MTP Shakers Journal Article

In: Methods in Molecular Biology, vol. 1685, pp. 145–156, 2018, ISSN: 10643745.

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2017

Younes, Sabry H. H.; Ni, Yan; Schmidt, Sandy; Kroutil, Wolfgang; Hollmann, Frank

Alcohol Dehydrogenases Catalyze the Reduction of Thioesters Journal Article

In: ChemCatChem, vol. 9, no. 8, pp. 1389–1392, 2017, ISSN: 18673899.

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Wedde, Severin; Rommelmann, Philipp; Scherkus, Christian; Schmidt, Sandy; Bornscheuer, Uwe T.; Liese, Andreas; Gröger, Harald

An alternative approach towards poly-epsilon-caprolactone through a chemoenzymatic synthesis: Combined hydrogenation, bio-oxidations and polymerization without the isolation of intermediates Journal Article

In: Green Chemistry, vol. 19, no. 5, pp. 1286–1290, 2017, ISSN: 14639270.

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Scherkus, Christian; Schmidt, Sandy; Bornscheuer, Uwe T.; Gröger, Harald; Kara, Selin; Liese, Andreas

Kinetic insights into ϵ-caprolactone synthesis: Improvement of an enzymatic cascade reaction Journal Article

In: Biotechnology and Bioengineering, vol. 114, no. 6, pp. 1215–1221, 2017, ISSN: 10970290.

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Böhmer, Stefanie; Köninger, Katharina; Gómez-Baraibar, Álvaro; Bojarra, Samiro; Mügge, Carolin; Schmidt, Sandy; Nowaczyk, Marc M.; Kourist, Robert

Enzymatic oxyfunctionalization driven by photosynthetic water-splitting in the cyanobacterium Synechocystis sp. PCC 6803 Miscellaneous

2017, ISSN: 20734344.

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Schmidt, Sandy; Almeida, Tiago Pedroso De; Rother, Dörte; Hollmann, Frank

Towards environmentally acceptable synthesis of chiral alpha-hydroxy ketones: Via oxidase-lyase cascades Journal Article

In: Green Chemistry, vol. 19, no. 5, pp. 1226–1229, 2017, ISSN: 14639270.

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Schmidt, Sandy; Gröger, Harald; Kourist, Robert

Durch Trennen verbinden Journal Article

In: Nachrichten aus der Chemie, vol. 65, no. 10, pp. 985–988, 2017, ISSN: 14399598.

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Rauch, M.; Schmidt, S.; Arends, I. W. C. E.; Oppelt, K.; Kara, S.; Hollmann, F.

Photobiocatalytic alcohol oxidation using LED light sources Journal Article

In: Green Chemistry, vol. 19, no. 2, pp. 376–379, 2017, ISSN: 14639270.

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Reimer, Anna; Wedde, Severin; Staudt, Svenja; Schmidt, Sandy; Höffer, Diana; Hummel, Werner; Kragl, Udo; Bornscheuer, Uwe T.; Gröger, Harald

Process Development through Solvent Engineering in the Biocatalytic Synthesis of the Heterocyclic Bulk Chemical epsilon-Caprolactone Journal Article

In: Journal of Heterocyclic Chemistry, vol. 54, no. 1, pp. 391–396, 2017, ISSN: 19435193.

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2016

Beier, Andy; Bordewick, Sven; Genz, Maika; Schmidt, Sandy; Bergh, Tom; Peters, Christin; Joosten, Henk Jan; Bornscheuer, Uwe T.

Switch in Cofactor Specificity of a Baeyer–Villiger Monooxygenase Journal Article

In: ChemBioChem, vol. 17, no. 24, pp. 2312–2315, 2016, ISSN: 14397633.

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Genz, Maika; Melse, Okke; Schmidt, Sandy; Vickers, Clare; Dörr, Mark; Bergh, Tom; Joosten, Henk Jan; Bornscheuer, Uwe T.

Engineering the Amine Transaminase from Vibrio fluvialis towards Branched-Chain Substrates Journal Article

In: ChemCatChem, vol. 8, no. 20, pp. 3199–3202, 2016, ISSN: 18673899.

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Scherkus, Christian; Schmidt, Sandy; Bornscheuer, Uwe T.; Gröger, Harald; Kara, Selin; Liese, Andreas

A Fed-Batch Synthetic Strategy for a Three-Step Enzymatic Synthesis of Poly-ϵ-caprolactone Journal Article

In: ChemCatChem, vol. 8, no. 22, pp. 3446–3452, 2016, ISSN: 18673899.

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Balke, Kathleen; Schmidt, Sandy; Genz, Maika; Bornscheuer, Uwe T.

Switching the Regioselectivity of a Cyclohexanone Monooxygenase toward (+)-trans-Dihydrocarvone by Rational Protein Design Journal Article

In: ACS Chemical Biology, vol. 11, no. 1, pp. 38–43, 2016, ISSN: 15548937.

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Dörr, Mark; Fibinger, Michael P. C.; Last, Daniel; Schmidt, Sandy; Santos-Aberturas, Javier; Böttcher, Dominique; Hummel, Anke; Vickers, Clare; Voss, Moritz; Bornscheuer, Uwe T.

Fully automatized high-throughput enzyme library screening using a robotic platform Journal Article

In: Biotechnology and Bioengineering, vol. 113, no. 7, pp. 1421–1432, 2016, ISSN: 10970290.

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2015

Schmidt, Sandy; Scherkus, Christian; Muschiol, Jan; Menyes, Ulf; Winkler, Till; Hummel, Werner; Gröger, Harald; Liese, Andreas; Herz, Hans Georg; Bornscheuer, Uwe T.

An enzyme cascade synthesis of epsilon-caprolactone and its oligomers Journal Article

In: Angewandte Chemie - International Edition, vol. 54, no. 9, pp. 2784–2787, 2015, ISSN: 15213773.

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Schmidt, Sandy; Büchsenschütz, Hanna C.; Scherkus, Christian; Liese, Andreas; Gröger, Harald; Bornscheuer, Uwe T.

Biocatalytic Access to Chiral Polyesters by an Artificial Enzyme Cascade Synthesis Journal Article

In: ChemCatChem, vol. 7, no. 23, pp. 3951–3955, 2015, ISSN: 18673899.

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Schmidt, Sandy; Genz, Maika; Balke, Kathleen; Bornscheuer, Uwe T.

The effect of disulfide bond introduction and related Cys/Ser mutations on the stability of a cyclohexanone monooxygenase Journal Article

In: Journal of Biotechnology, vol. 214, pp. 199–211, 2015, ISSN: 18734863.

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Schmidt, Sandy; Scherkus, Christian; Muschiol, Jan; Menyes, Ulf; Winkler, Till; Hummel, Werner; Gröger, Harald; Liese, Andreas; Herz, Hans-Georg; Bornscheuer, Uwe T

Eine Enzymkaskade zur Synthese von epsilon-Caprolacton und dessen Oligomeren Journal Article

In: Angewandte Chemie, vol. 127, no. 9, pp. 2825–2828, 2015, ISSN: 1521-3757.

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